Tag: research
All the articles with the tag "research".
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Ch. V — Clinical evidence: depression and anxiety
Psilocybin TRD and MDD; LSD anxiety; MM120 GAD; meta-analytic comparison; Cochrane RoB 2.0 critique; ketamine as comparator.
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Post-2010 Psychedelics: An Expert-Panel Review
A ~65,000-word, thirteen-chapter interdisciplinary review of post-2010 psychedelic developments — clinical evidence, receptor biology and neuroplasticity, regulatory landscape, methodology critique, and sociocultural context including Indigenous reciprocity. Verified-citation, placebo-honest, post-Lykos.
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Ch. III — Receptor biology and signaling bias
Why 5-HT2A is necessary but not sufficient; Gq vs β-arrestin; the 2022–2025 cryo-EM atlas; the non-hallucinogenic 5-HT2A agonist frontier.
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Ch. XI — Regulatory and legal landscape
US federal status; FDA BTD timeline; the Lykos regulatory episode; Oregon Measure 109; Colorado Prop 122; Australia, EU/UK, Canada; pharma economics; REMS architecture and DEA scheduling.